Catalytic Reaction Guide

Expert guidance for catalyst selection across major reaction classes. Navigate the complexity of modern catalysis with our comprehensive technical resources and application notes.

Hydrogenation

Reduction of C=C, C=O, C=N, aromatics, and nitro groups. Catalyst selection for Pd, Pt, Ru, Rh, and Ni systems under diverse conditions.

Pd/C Pt/C Raney Ni

Cross-Coupling

Suzuki, Heck, Negishi, Stille, and Buchwald-Hartwig reactions. Palladium catalysts and ligand optimization for challenging substrates.

Pd Complexes Phosphines

Oxidation

Selective oxidation of alcohols, aldehydes, and C-H bonds. Catalytic systems for aerobic oxidation and peroxide-mediated transformations.

Ru Catalysts Mn Oxides

C-C Bond Formation

Aldol, Michael additions, and cycloadditions. Organocatalysts and metal complexes for stereoselective carbon framework construction.

Organocatalysts Lewis Acids

Asymmetric Hydrogenation

Enantioselective reduction with chiral catalysts. BINAP, DuPhos, Josiphos systems for pharmaceutical intermediates with >99% ee.

Rh-BINAP Ru-DuPhos

C-H Activation

Direct functionalization of C-H bonds. Pd, Rh, Ir, and Ru catalysts for arylation, alkylation, and borylation reactions.

Pd Catalysts Ir Complexes

Transfer Hydrogenation

Reduction using hydrogen donors instead of H2 gas. Safer alternative for ketone and imine reduction using isopropanol or formic acid.

Ru Complexes Ir Systems

Metathesis

Olefin cross-metathesis, ring-closing, and ring-opening metathesis polymerization. Grubbs and Hoveyda-Grubbs catalyst systems.

Grubbs I/II Hoveyda

Carbonylation

Incorporation of CO into organic molecules. Hydroformylation, carbonylative coupling, and Monsanto/Cativa acetic acid processes.

Rh Catalysts Pd Complexes

Biocatalysis

Enzyme-catalyzed transformations for green chemistry. Ketoreductases, transaminases, and hydrolases for pharmaceutical synthesis.

KREDs Lipases

How to Use This Guide

1

Select Reaction Type

Choose the catalytic transformation you need from the reaction categories above.

2

Review Catalyst Options

Explore recommended catalysts, conditions, and substrate scope for your application.

3

Contact Our Experts

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