Technical Downloads

Access comprehensive technical documentation for our catalyst products and services. All documents are provided in PDF format for easy viewing and printing. For additional technical resources not listed here, please contact our technical support team.

Product Data Sheets

Detailed technical specifications, handling instructions, and application guidance for our catalyst products.

Heterogeneous Catalysts

Palladium Catalysts

• Palladium on Carbon (5%) - Product specifications, handling, and typical applications
• Palladium on Carbon (10%) - High-loading formulation for demanding applications
• Palladium on Alumina - Alternative support for specialized applications
• Sulfur-Tolerant Palladium Catalysts - Formulations for challenging substrates

Platinum Catalysts

• Platinum on Carbon (5%) - Standard formulation for selective hydrogenation
• Platinum Oxide (Adams Catalyst) - High-activity catalyst for ketone reduction
• Platinum on Alumina - Specialized applications and aromatic hydrogenation

Other Precious Metal Catalysts

• Rhodium on Carbon - Challenging hydrogenations and basic substrates
• Rhodium on Alumina - Alternative formulation with distinct selectivity
• Ruthenium on Carbon - Selective aromatic reduction and oxidation
• Raney Nickel - Non-precious metal alternative for large-scale applications

Homogeneous Catalysts

Asymmetric Hydrogenation Catalysts

• Rhodium-BINAP Complexes - Enamide and functionalized olefin reduction
• Ruthenium-BINAP Complexes - Ketone hydrogenation and beta-keto ester reduction
• Rhodium-DuPhos Catalysts - High-selectivity pharmaceutical intermediates
• Rhodium-BPE Systems - Complementary selectivity to DuPhos ligands
• Iridium-Josiphos Catalysts - Unfunctionalized olefin reduction

Cross-Coupling Catalysts

• Palladium-Phosphine Complexes - Suzuki and Heck coupling applications
• Specialized Buchwald Precatalysts - Challenging cross-coupling reactions
• Palladium-NHC Complexes - Enhanced stability and activity

Metathesis Catalysts

• Grubbs First Generation - Standard olefin metathesis applications
• Grubbs Second Generation - Enhanced activity and substrate scope
• Hoveyda-Grubbs Catalysts - Improved stability and recyclability

Chiral Ligands

Phosphine Ligands

• (R)-BINAP and (S)-BINAP - Axially chiral binaphthyl phosphines
• (R,R)-DuPhos and (S,S)-DuPhos - C2-symmetric bis(phospholane) ligands
• Josiphos Family - Ferrocenyl ligands with tunable properties
• SEGPHOS - Conformationally flexible BINAP analogs

Advanced Ligand Systems

• Buchwald Ligands (SPhos, XPhos, RuPhos) - Bulky electron-rich phosphines
• DavePhos and tBuXPhos - Specialized cross-coupling applications
• NHC Ligands - N-heterocyclic carbene donors

Biocatalysts

Ketoreductases (KREDs)

• KRED Library Overview - Substrate scope and selectivity patterns
• Individual KRED Data Sheets - Specific enzyme variants and applications
• Cofactor Regeneration Systems - NADPH recycling technologies

Transaminases

• Transaminase Portfolio - Chiral amine synthesis capabilities
• (S)-Selective and (R)-Selective Variants - Complementary stereoselectivity
• Application Guidelines - Reaction optimization and scale-up

Hydrolases

• Lipases and Esterases - Ester synthesis and resolution
• Protease Variants - Amide bond formation applications

Safety Data Sheets (SDS)

Material safety information complying with globally harmonized system (GHS) requirements.

Precious Metal Catalysts

• All palladium, platinum, rhodium, and ruthenium catalyst formulations
• Regional versions available (US, EU, Asia-Pacific)
• Updated to current regulatory standards

Organometallic Complexes

• Rhodium and ruthenium complexes with chiral ligands
• Palladium pre-catalysts and phosphine complexes
• Grubbs and Hoveyda-Grubbs metathesis catalysts

Biocatalysts

• Enzyme formulations and storage requirements
• Cofactor materials and regeneration systems

Application Notes

Practical guidance for implementing catalytic methodologies in pharmaceutical synthesis.

Hydrogenation Applications

• Olefin Hydrogenation Best Practices - Catalyst selection and condition optimization
• Aromatic Ring Reduction - Platinum and rhodium catalyst comparison
• Nitro Group Reduction - Selectivity and functional group tolerance
• Protecting Group Removal via Hydrogenolysis - Benzyl ether and carbamate cleavage

Asymmetric Synthesis

• Asymmetric Hydrogenation for Pharmaceutical Intermediates - Case studies and catalyst selection
• Achieving High Enantiomeric Excess - Optimization strategies
• Dynamic Kinetic Resolution - Beta-keto ester applications
• Scaling Asymmetric Hydrogenation - From lab to manufacturing

Cross-Coupling Reactions

• Suzuki Coupling Optimization - Base, solvent, and ligand selection
• Challenging Cross-Coupling Substrates - Hindered and electron-rich coupling partners
• Buchwald-Hartwig Amination - Catalyst and ligand pairing
• Heterocycle Synthesis via Cross-Coupling - Pharmaceutical applications

Oxidation Chemistry

• Alcohol Oxidation Methods - Catalyst comparison and selectivity
• Aerobic Oxidation with Palladium Catalysts - Green chemistry approaches
• C-H Oxidation for Late-Stage Functionalization - Site selectivity considerations

Biocatalysis

• Introduction to Biocatalytic Synthesis - Benefits and implementation
• Ketoreductase Screening Protocols - Identifying optimal enzymes
• Transaminase Applications in Pharmaceutical Synthesis - Chiral amine building blocks
• Enzyme Immobilization for Continuous Processing - Technology and benefits

Analytical Methods

Validated analytical procedures for quality control and characterization.

Metal Content Determination

• ICP-MS Methods for Precious Metal Quantification
• Residual Catalyst Analysis in Pharmaceutical Products
• Compliance with ICH Q3D Elemental Impurity Guidelines

Enantiomeric Excess Determination

• Chiral HPLC Methods - Separation and quantification
• Chiral GC Techniques - Volatile compound analysis
• Optical Rotation Measurements - Classical chiroptical methods

Product Purity Analysis

• HPLC Assay Methods - Quantitative product analysis
• Impurity Profiling - Related substances identification
• NMR Spectroscopy - Structural confirmation

Regulatory Documentation

Supporting information for pharmaceutical regulatory submissions.

Drug Master Files (DMFs)

• Type II DMFs for major catalyst products
• Updated regulatory information and manufacturing details
• Letter of Authorization templates for customer reference

Certificate of Suitability (CEP)

• European Pharmacopoeia compliance documentation
• Available for key pharmaceutical catalyst products

Quality Agreements

• Template quality agreements for GMP applications
• Specifications and testing protocols

Technical Guides

Comprehensive resources covering catalysis fundamentals and advanced topics.

Catalysis Fundamentals

• Introduction to Heterogeneous Catalysis - Principles and applications
• Homogeneous Catalysis Overview - Mechanism and catalyst design
• Asymmetric Catalysis Concepts - Stereocontrol in synthesis
• Biocatalysis Primer - Enzyme catalysis for pharmaceutical applications

Process Development

• Catalyst Screening Strategies - Systematic optimization approaches
• Scale-Up Considerations - Laboratory to manufacturing transition
• Safety in Catalytic Processes - Hazard assessment and mitigation
• Environmental Aspects of Catalysis - Green chemistry and sustainability

Troubleshooting Guides

• Common Issues in Hydrogenation - Diagnosis and solutions
• Cross-Coupling Problem Solving - Addressing low yields and selectivity
• Optimizing Asymmetric Reactions - Improving enantioselectivity

Webinars and Presentations

Recorded educational content from our technical experts.

Recent Webinars

• Advances in Asymmetric Hydrogenation (2024)
• Green Chemistry through Biocatalysis (2024)
• Modern Cross-Coupling Methodologies (2024)
• C-H Activation for Drug Discovery (2025)

Conference Presentations

• Selected presentations from major scientific conferences
• Case studies and application examples

Request Custom Documentation

Need specific technical information not listed here? Our technical team can provide:

• Custom application notes for your specific substrates
• Process optimization reports and recommendations
• Regulatory support documentation
• Training materials and technical presentations

Contact Technical Support:

• Email: technical@jmcct.com
• Phone: +1-800-CATALYST
• Online: Complete the contact form

All technical documents are proprietary to Johnson Matthey Catalysis & Chiral Technologies. By downloading, you agree to use the information solely for evaluation and implementation of our products in accordance with our Terms of Use.